What Is Delayed Onset Muscle Soreness (DOMS) & How Can Nutritional Intervention Reduce It? Every bead of sweat in your gym sessions is your battlefield, it lifts your spirit and your body is shown to progress. Lifting heavy and feeling tired keeps you stronger today, and makes you an achiever tomorrow. You met your better version with a more focused, motivated, and energetic you.  Your endurance means combined acceptance of your ability to tolerate pain and pursue your goals. Accepting temporary pains will bring eternal pride. It’s your glory, made of courage, perseverance, and sacrifice.  If you push harder today till you feel pain and intense soreness in your muscles, you start feeling good, so we better say “Pain is good once you achieve a desired physique”. And..your solid strength training routine keeps your muscles getting stronger.  It’s a deletion to say that….”Champions are those who refuse to give up.”  It is incumbent upon us to take the reference of eight-times Mr Olympia titled Ronnie Coleman “The King of Bodybuilding”, once he said “There’s no secret formula. I lift heavy, work hard, and aim to be the best.”  Every push of your perceived limits and beat them through the act of repeated challenge – you shall gain. And shall pay a heavy price for your sweat, pain, and you become tired. Success is accepting pain through a series of events. No pain resulting in no gain. If your body isn’t prepared, you ought to be prepared to fail again on the next day. So, wake up, the clock is ticking. Would you like to become the person you want to be? Read this very important discussion that gives you really hard success.  Have you ever crushed your first workout sessions in your new training phase or made a return to a workout routine after a break, and then woke up the next day, you had some time off from the workout after you felt the pain?   You know that feeling when you wake up the morning after a killer workout and every single muscle in your body is screaming at you? Yep, that’s what we call delayed onset muscle soreness, or DOMS for short. It’s known as ‘muscle fever’, it’s your muscle soreness, muscle starts aching (myalgia) for a few days after a workout, feel pain in the muscles, these commonly occur after strenuous or eccentric exercises.   Is DOMS Normal And How Do You Manage It?  You were likely wondering about the source of your intense pain, weren’t you? It’s your body’s way of telling you that you really worked those muscles hard – and that’s a good thing! See, when you push yourself harder in the gym and lift those heavy weights, you’re actually causing little tears in your large multinucleated cells in the muscles and start feeling stiffness. After that, during resting time, your body then rushes in to start repairing breakdowns, and this could lead to your muscles getting bigger and stronger day after day.  Your muscle repair process leads to insane soreness for the next day. That’s how you build muscle, and you will get that shredded physique if you eat proper nutrition after that phase. Exercise-induced muscle damage (EIMD) is very common after your eccentric exercises such as cycling, weight pulling, wrestling, jogging, running, high-impact step aerobics, rope jumping, swimming, cycling, high-intensity walking, etc. give your muscle pain, temporary muscle damage (soreness), low range of motion (ROM), tight feelings, muscle tissue destruction, inflammation, and lower muscle function.   These unfavorable consequences may trigger pain in muscles, and disrupt subsequent time-to-task athletic performance failure and lower self-paced endurance or pace of training quality, especially in individuals who have less recovery time for the next bout or training sessions.  The way we see it, if you’re not feeling muscle soreness after your strenuous exercise sessions, you probably didn’t work hard enough.  Lifting heavy and feeling fatigued after every heavy workout session keeps you build better muscle and feel stronger tomorrow. Your endurance and ability to accept and push through that pain make you a real champion and proclaim your extravagant glory.  When And How DOMS Occur? Let me clear you, the real workout starts when you want to give up. Your noticeable muscle gains occur through forceful contraction during the time of your very last few reps. So, push harder, refuse to quit, and enjoy your fitness most. That’s where the magic happens, my friend. That’s where you’ll find the gains, the strength, the pride.  There’s a tried-and-true formula here – lift heavy, work your butt off, and aim to achieve your best version. This pain is temporary, success in building better muscle is permanent, so being well will never be denied.  You have been often tried and ready to try again, which makes you a real champion. You have to push your perceived limits, the limits you thought were as far as you could go. It’s not easy, but the payoff is so worth it. Understanding DOMS: How Nutrition and Supplements Can Aid Recovery After Exercise! The interest of Delayed Onset Muscle Soreness (DOMS) has intrigued sports scientists for years. There have been six different hypothesised theories proposed for the contribution to DOMS, such as lactic acid, muscle tightening, inflamed tissue, inflammation, efflux of muscle enzymes theories, and structural muscle damage, alongside, nitric oxides decreased muscle force generation, perturbed calcium homeostasis, inflammatory responses, free radicals, all these causing DOMS. Understanding the mechanisms behind DOMS is crucial for athletes and fitness enthusiasts looking to optimise their recovery process. When you engage in strenuous exercise, especially activities that involve eccentric muscle contractions, resulting in morphological damage induced by eccentric contractions, and you start feeling DOMS, this could occur around 24-48 hours after the finish of your physical activity or post-exercise.  Chemokines are secreted by cells after muscle damage, this could trigger inflammatory cells (such as neutrophil and macrophages) to become more active.  On this, your muscles become swollen, tender, and weaker strength output, these could greatly influence to

Best Nutritional Health Supplements For Keeping Your Prostate Healthy and Manage Symptoms? Yes, we know it’s not a very ‘talked-about’ topic, but trust me, it’s essential, especially for people aged over 50. So, what’s the discomfort feeling in the prostate, does your doctor tell you have an enlarged or swollen prostate – your frequent urination during the day and night or sudden urges to pee cause an overactive bladder (bad prostate health) might put you back or that it’s almost entirely hard to accept the reality? Well, for men over the age of 50, annoying urination issues caused by an enlarged prostate are very common. But not to worry about, nutritional supplement adjustments for an enlarged prostate reduce the likelihood of keeping your prostate healthy. Keep your diet in check or malnutrition including vitamin D, B6, or B12, is commonly found in older adults. Especially, older age decline in the efficient absorption of vitamin B12 (complex interplay) in the stomach, pancreas, and small intestine. Knowing how to improve your prostate health is advantageous and helps you lower your chance of developing certain prostate problems.  Did you know that making smart lifestyle choices can naturally boost your prostate health? Yep, a well-documented has summarised that simple lifestyle changes such as maintaining a healthy weight, eating a balanced diet, checking your hormonal balance, cutting down on alcohol and processed foods, and the inclusion of regular physical activity can do miracles for your prostate health and may also help lessen your risk of advanced or aggressive prostate issues. Now, let’s get into this small gland is made of connective tissues and glandular tissues – your prostate plays a big role in the male reproductive system and contributes to the production of fluid to make semen more watery to nourish sperm and helps retrograde ejaculation through your penile urethra during sexual arousal. As we age, the risk of developing prostate issues, such as an enlarged prostate or even in extreme cases prostate cancer may ramp up. But, there are a few steps you can take to keep your prostate happy and healthy. The prostate is a small muscular gland especially found only in men and a walnut-shaped organ, located below the bladder, that encircles the urethra and in front of the rectum. Fun fact: the name ‘prostate’ comes from the Greek word prostátēs (προστάτης), meaning ‘one who stands before.’ Its principal job is the production of whitish fluids mixed with sperm to make semen. Prostate muscles forcefully push semen through the duct system and male urethra, which is passed through a roughly 18-22 cm long narrow fibromuscular tube that links with the urinary bladder and moves through the prostate gland, then throws semens outwards during male sexual stimulation (ejaculation time). Are you having an enlarged prostate? Many research suggests a link between poor health and a higher risk of developing prostate cancer or other prostate-related diseases. If you have an enlarged prostate, also called benign prostatic hyperplasia (BPH), it can bring a lot of challenges. It is closely linked with urinary troubles, less likely to feel comfort, sleep disruptions, embarrassment, and anxiety, it can really affect your daily life. But don’t worry, making some lifestyle changes can help you manage those symptoms and improve your quality of life, especially by tweaking your nutritional content. Recent studies have shown that many men over 50 years of age in the UK, Germany and France, three in 4 men (74%), aren’t fully unaware of the role and functions of the prostate. In that study, only 26 percent of respondents are only aware of enlarged prostate disorders and knew the prevalence of prostate-related issues. Health experts emphasise the importance of understanding a healthy prostate, especially with the ageing population growing the risk of developing an enlarged prostate is not linked with a “normal” sign of getting older. This investigation shocked professional urologist Prof. Hein Van Poppel, former Director of the European School of Urology and currently holding the post of Adjunct Secretary General for the EAU (European Association of Urology), who expressed his concern about worrying risk of surveying male age groups most likely to have prostate-related conditions including enlarged prostate and prostate cancer. So, dear readers, take care of your prostate health – a little effort now can go a long way in keeping you healthy later on! Guide to Prostate Supplements & Enlarge Prostate Symptoms: For men’s health, one area that often gets overlooked is prostate health. Anatomically, prostate is a walnut-sized gland found below the bladder that plays a crucial role in male reproductive mechanism. Despite its importance, many men are unaware of the warning signs of prostate issues and the potential risks they have. As men when age, unhealthy lifestyle, obesity, and hormonal changes can lead to an enlarged prostate, a common condition known as benign prostatic hyperplasia (BPH). This prostate enlargement can cause various symptoms such as a frequent urge to pee (overactive bladder (OAB), difficulty starting to urinate stream (Urinary Hesitancy), involuntary loss of urine, and a sensation of incomplete bladder emptying (urinary retention). Surprisingly, nearly half of men aged 50-60 are unfamiliar with these signs, which can have alarming consequences on their overall health. Research indicates that men with moderate to severe symptoms of BPH are at a higher risk of developing serious heart conditions, including strokes and cardiac death. Knowing these symptoms and getting quick medical checks can easily deal with the early detection and treatment of prostate issues. If you experience frequent urination, pain or burning sensations during urination, or blood in urine or semen, it’s important to consult with your doctor immediately. Before catching these symptoms or to address any prostate health concerns, many above 50-year-old men turn to nutritional health supplements, especially prostate support supplements that are specifically formulated to promote prostate health. These prostate support supplements often contain a blend of vitamins, minerals, and many other bioactive compounds that are believed to support overall prostate health. Some of the highly used ingredients found in these

Don’t Get Enough Sleep? DIFFICULT FALLING ASLEEP IS VERY COMMON IN OLDER ADULTS! A good nap is a dream of many, and older adults vividly crave it. A power nap may boost our bodies’ ability to improve physical performance, lift our mood, make us more alert, and control stress. So, sleep is not just a luxury or a tired obligation (drained in energy) but a vital addition to our well-being across all ages. The number of older adults in the United States (65 years or above) is set to double in the next 25 years. By 2030, roughly every fifth of people in the US will be 65 years old or above. Shrinkage in nocturnal sleep duration is common with age, and many sleep disorders will arise. The rate of sleep problems in older adults (up to 50%) is much higher than in the general population (15.9-22.3%). These changes to poor sleep patterns often contribute to a preponderance of medical and psychiatric comorbidities, with the additional effects of polypharmacy. So, the importance of quality sleep becomes even more pronounced among elderly people. Electrophysiology is a study of electrical aspects of physiological phenomena, it has split into two distinct stages of sleep: Stage 1 is Non-Rapid Eye Movement (NREM) sleep also named ‘quiescent sleep’ and stage 2 is Rapid Eye Movement (REM) sleep also called as ‘paradoxical sleep’, these two can be characterised human sleep patterns. Research suggests that sleep influences many bodily functions on various levels – sleep plays a big role in the modulation of molecular genetics and synaptic transmission at a cellular level, immunometabolism processes and cognitive functions on a more organised scale. So many studies suggest that the multi-dimensional role of sleep plays at cellular to organ levels to maintain the self-regulating optimal function in our brain and body. Sleep deprivation may cause many health challenges: Although sleep-wake syndrome of less than 4 hours of sleep time per day for a few days may likely develop a nuisance, however, chronic sleep deficiency can have far-reaching effects with severe health complications in young as well as in older adults. It may lead to mood swings, extreme fatigue, poor sleep-wake cycle (Circadian rhythm disorders), long-term insomnia, cognitive deficiency, low or extreme appetite, intense desire for carbohydrate food, low sex drive, and many host of other complications that can occur from prolonged lack of quality sleep. Persistent sleep deprivation can lead to daytime drowsiness, which increases risks of cognitive decline, increased falls, and many serious health issues among elderly people. Patients with sleep disorders may also be at a higher risk of developing cardiovascular problems, the intricate relationship between sleep and overall health. The prevalence of disrupted sleep causes immediate health concerns, often worsening many medical conditions, including obesity, stroke, type 2 diabetes, trauma, depression, and hypertension, all of which or alone, can contribute to a highly severe or poor quality of phenomenon in life. How much adequate amount of quality sleep do we need daily? Therefore, we must understand why does the optimal amount of quality sleep daily is needed by our bodies. The ‘National Sleep Foundation’ (NSF) USA recommends 7-9 hours of sleep each day for younger adults (18–25 years) and 7-8 hours for older adults (26–64 years) to support their overall well-being. Up to 70 million people in the US & 45 million European adults don’t get enough sleep: According to sleep medicine specialist Dr. Nancy Foldvary-Schaefer, sleep is essential for overall health, especially for heart health, metabolic health, and brain health. So what happens when you miss out on sleep besides feeling groggy and oversleeping? Let’s understand the various effects of sleep deprivation. As we age, our sleep patterns change. While some older adults keep their sleep routines, but a large number of older adults face issues like ‘Circadian rhythm disorders’, a change in body clock, leading to early tiredness and rising ahead of schedule. Many experts have shown that older adults experience similar sleep issues. Moreover, ageing can disturb our sleep architecture, it’s called stages of sleep-wake cycle disorders – we cycle through in sleep. Ageing causes tend to spend more time in lighter sleep stages and find a harder time falling asleep, which could lead to frequent awakenings and disturbed sleep. It’s very common for older adults to nap during the day, with around 25% of older adults taking naps in the daytime compared to 8% of younger adults taking short sleep periods during the daytime.   Many researchers argue that a nap time after 3 p.m. could disrupt your sleep soundly at night. While a short daytime nap can be beneficial, excessive daytime sleepiness or later-day napping can interfere with falling asleep at night and lead to sleep deprivation or obstructive sleep apnea (OSA). Fix Your Sleep Schedule With the Power Of Natural Herbs: Too much use of sedative-hypnotic drugs (Prescription Insomnia Drugs – depressants) over a long period has various side effects, including negative impacts on cognitive function and reduced daytime wakefulness. However, in recent years, there has been a growing interest in natural sleep aid herbal supplements such as Valeriana officinalis extract and chamomile extract, endorsed by the European Medicine Agency (EMA), which are renowned for their ability to relieve mild nervous breakdown and sleep disorders. For mental relaxation, they proposed that taking 300 milligrams of daily Valeriana officinalis root extract may improve sleep quality. Chamomile extract: Chamomile aqueous extract has a rich history as a mild sedative, aids in calming nerves, reduces anxiety, controls outbreaks of Hysterical Signs, and addresses various sleep-related issues, from nightmares to insomnia. A meta-analysis of 12 trials has found that chamomile has a positive impact on sleep quality, mainly because it has a flavonoid called apigenin that induces a mild calming effect or works as a tranquilliser. It has also been demonstrated that helped insomnia patients to improve daytime alertness, as well as promote sleep in women during menopause and after pregnancy. L-theanine: Another natural herb has been used as a likely aid for mental relaxation

Our Favorite Nutritional Support For Mums USA From Supremo Nutrition’s 45% Off Mother’s Day Sale! Mother’s love is always touchy and divine to us. There is nothing as delicate as a mother’s kiss; this form of love is as emotional blunting as any form of love, and we have felt the stream of her love every day, and it is pouring on us.  Her strength is truly inspiring us, and we’re always overjoyed to hear about her well-being! There are so many people cheering for her good health. Thank you for guiding us on how to meet challenges to achieve our lives and careers.  As Mother’s Day is just knocking on the door, it’s a race against the clock to find Mother’s Day gifts for the disguised superwoman in your life. If you want to pick up something she’ll adore that’s also on your budget, don’t worry, we’ll help you find the best health gifts for mum USA on your Mother’s Day celebration in 2025. Why not think of giving your mom the best dietary supplements for women? Ahead of time, buy Best Health & Nutritional Supplements for Mom’s Day gifts to save 45% on the best Mother’s Day discounts on health products USA. Shop for Mother’s Day health gifts USA from a health and wellness brand to help her promote her well-being. These are plant-derived nutraceuticals as dietary supplements for all women, at any age, to support their health and fitness journey. We’ve rounded up the best Mother’s Day special offers on supplements USA on all nutraceuticals “From Nature To Your MOM” – now you can get them at a 45% discount on nutritional supplements online. Just make sure to check the shipping details before you place your order. Use the promo code: SNMOMS50 to get instant 45% OFF, and it’s applied at your checkout.  Higher Microbiological Quality Of Bioactive Compounds! Most European populations are aging faster, and plant-derived dietary supplements, especially support optimal health, have become increasingly popular among many generations. These plant-extract nutraceuticals have potent bioactive compounds, such as all forms of vitamins, minerals, amino acids (essentials & non-essentials), herbs fatty acids, and botanicals, and more, which bring specific health benefits due to their microbiological quality help better absorb the nutrients in bodies, particularly for elderly individuals lacks or suffering from nutritional deficiencies. The prevalence of polypharmacy is closely linked to community-dwelling older age groups and in inpatient settings due to multimorbidities. The abrupt or excessive use of polypharmacy can lead to adverse drug effects, including increases in the risk of insomnia, oversedation, fractures, drowsiness or confusion, orthostatic hypotension (sudden falls), sarcopenia, angina pectoris, and degraded cognitive functions, which cumulatively can enhance drug-dependency. However, early and regular use of the best nutritional health & dietary supplements can reduce drug-drug interactions, and lower the dependency of polypharmacy, which are typical health issues among older people. Best nutritional supplements to support overall health! The best supplement for overall health can be beneficial at any age, offering nutrients to support bone health, improve gut health and liver functions, boost overall wellness, or lower your risk of many health problems such as osteoporosis, arthritis, support cardiovascular health, improve cognitive functions, boost sleep cycles, helps better irregular menstrual cycles and maintain a healthy weight, support to control menopausal symptoms, improve immune systems, and so on this list. These healthy nutrition supplements can replenish health nourishing nutritent gaps in your daily life. They can be picked up without a doctor’s prescription, but it’s necessary to understand the purpose of these healthy supplements you’re going to gift to your moms and why you should take them. Why do we need to add nutritional health supplements to our daily diets? In 2019, according to the United Nations, the faster growth in population aging became a serious social transformation in the current century. They made a statement that the growing number of older adults population is 65 will double by 2050, and this number will go up to triple by 2100. The growth of the aging cycle will go up from 962 million in 2017 to an increase of 99.78% (2.1 billion) in 2050 and a 99.67% increase (3.1 billion) in 2100. As Europe’s population ages faster, it puts stress on a higher chance of age-related diseases, and a lack of dietary attention could trigger many health complications, including: Physiological changes in older adults lead to decreased nutrient consumption and poor absorption of essential nutrients, which could cause vitamin and mineral deficiencies. Rise in age-related illnesses and increased medication consumption or prevalence of multi-medication use in older adults, we need a better dietary plan to address these concerns as a top priority. On average, one in ten patients undergoing hospital care in high-income countries is prone to dealing with multiple adverse pharmacological effects based on current drug habits. Therefore, we need to pay attention to giving them dietary health and nutritional supplements for healthy aging. This Mother’s Day, consider the gift of good health. By offering discounted health products for mum USA on the best dietary supplements, you can help nurture your mother’s well-being, your thoughtful and caring gesture that goes beyond the vintage-inspired textiles or any other forms of heritage gifts. To any woman – you’re celebrating this Mother’s Day 2025—especially for moms—will appreciate their great contribution to our society, and these Mother’s Day health gifts USA can improve your health and provide antioxidant support in all seasons. Made from plant-derived nutrients, it gives superb health benefits in multiple health complications. You can never go wrong with gifting wellness gifts for mums USA during Mother’s Day Celebration in 2025. Therefore, ensuring the best possible nutritional support for older people can meet the gaps in nutritional deficiencies or check malnutritional status with the right nutrients. Check out Supremo Nutrition’s Mother’s Day special offers on supplements USA – you all are entitled to get 45% OFF on healthy nutrition supplements. Just shop for wonderful Mother’s Day gifts and love her more than any words you can

Why Amino Acids and Multivitamins Supplements are Essential for All Adults To Be Healthy? A protein molecule (known as polypeptide chains) consists of long chains of amino acids that are the building blocks to shape all living organisms. They certainly do many vital biological processes to bodily functions like supporting muscle growth, contributing to brain health, promoting long-term energy, and promoting tissue repair and active recovery after intense physical activity.   To act optimal body functions, our bodies require all 20 different types of amino acids, these are essential nutrients and indispensable in our life. But, to actually grasp the significance of protein in our body, we need to find an objective in a protein molecule that makes it up – it’s a long chain of amino acids. These are the fundamental building blocks of protein, synthesised within the body (there are nine amino acids considered as “essential”) – as obtained through our diet. When it’s bound together, it form a protein. Why essential & non-essential amino acids are: Important & foods? Amino acids are mostly composed of certain organic compounds – oxygen, nitrogen, and hydrogen, with a major “alpha carbon“. Amino acids play a role above just the components of protein synthesis. They aid in hormone production, support gut health, help create neurotransmitters, and regulate certain physiological processes. Their enormous benefits emphasise the importance of maintaining adequate levels of amino acids. These amino acids, such as leucine, DL-methionine, L-Histidine, isoleucine, L-Threonine, L-Phenylalanine, valine, histidine, lysine, L-Tyrosine, L-glutamic acid, L-Arginine, L-Aspartic Acid, L-Alanine, L-Serine, L-proline (a nonessential amino acid, functions in energy metabolism and helps in protein biosynthesis and structure), L-Cysteine and L-Tryptophan, few among them aren’t synthesised by our human body, therefore we obtain dietary supplements or other food source nutrients to supply them. Each amino acid has a specific function; for example, leucine activates protein synthesis, while valine controls blood sugar and aids energy production.  The quality of protein varies, which requires a deeper understanding of amino acids. By taking all essential and non-essential amino acids as a considering subject, we can better appreciate their essential role in various bodily functions.  What & how do amino acids work in your body? Amino nitrogen is made of roughly 16% of the proteins’ weight. It’s nearly impossible to find a bodily process not dependent on amino acids. Your ability to [the following text] is largely influenced by amino acids, however, you get from – source (either made from yourself, food source, or store-bought supplements). Amino acids greatly influence our bodies’ ability to: Improve the digestive system, Transport of distributing nutrients, Control or innate immune response, Boost energy levels, Build muscle, Boost collagen (hair and nails), Cellular repair and healing wounds, Improve quality sleep, Produce enzymes and break down nutrients, Neurotransmitters Produce hormones (testosterone, estrogen, cortisol, and oxytocin), Regulate metabolic pathways. Food sources of amino acids are do we primarily get from meat, fish, and soybeans. Some people also prefer to take essential amino acids supplement form as a most trusted source to boost active sports performance, improve post-workout recovery cycle, and improve mood. Adequate Protein Requirements for Different Age Groups! So, to figure out how much protein young guys need, a bunch of studies were conducted by WHO in 1985. They undertake short and long-term studies to recommend that these young men should get around 0.75 grams of daily allowance of protein per kilogram of body weight. How much protein is needed for women? Well, not as much data is out there for young adult women, but it seems their protein needs are about the same as the guys. So, for both men and women in this group, 0.75 grams of protein per kilogram of weight each day should do the trick (Calloway and Kurzer, 1982). How much protein intake is recommended for older people? As we get older, our body changes occur and lose some muscle mass and strength. Whereas, in older adults, muscles start shrinking and getting replaced by fat. This whole muscle protein synthesis or degradation starts (Uauy et al., 1978a) as we get older, making us less responsive to the anabolic stimulus for the elderly than for younger adults. So, taking protein-rich diets in elderly people can help control higher-than-average serum albumin levels and normal daily albumin synthesis (Gersovitz et al., 1980). And you know what? It’s not clear so far how these changes affect how much protein older folks should be chowing down on. While Cheng et al. (1978) deemed 0.8 g of egg protein per kilogram of body weight daily sufficient, on the other hand, Gersovitz et al. (1982) reported it insufficient for maintaining nitrogen balance in a 30-day study of elderly people. There’s been some back and forth in the research, there we’ve noticed different studies showing different outcomes. But as it is, we recommended such as taking to 0.75 grams of protein per kilogram rule could be a good plan for both the young and the elderly. So, it looks like whether you’re a young ‘un’ or ‘une’ of the more seasoned members of our society, getting that protein in is super important. Just make sure to keep an eye on your intake, especially as the years go by! Who knew something as simple as proteins could play such a big role in our health journey? So, what are your thoughts on protein needs at different stages of life? Write in the comments or email us -so we discuss this further. Unpacking the Advantages of Ultimate BCAA Powder in the Fitness World! Ultimate BCAA Powder and its wide advantage in fitness and giving noticeable results in the bodybuilding community is the buzz, everyone is talking about. Athletes and fitness enthusiasts often turn to a pre workout supplement to optimise their athletic performance and reach their fitness goals, with one standout being ‘Ultimate BCAA pre workout powder’. Let’s check below on how it helps in fitness;  1..Ability to Improve Muscle Protein Synthesis! Among the excellent benefits of BCAAs in the fitness domain for

The rise of GLP-1 agonist drugs in Type 2 diabetes and anti-obesity. DOES IT SAFE TO CONSUME LONGER TIMES? Glucagon-like peptide-1 (GLP-1) agonists belong to pharmacological use that helps to treat Type 2 Diabetes Mellitus (T2DM) and in some cases, support the weight loss journey among overweight adults. Many healthcare providers now suggest as effective weight loss and type 2 diabetes treatment drugs. Since ADA (American Diabetes Association) and FDA confirmed that apart from metformin in Type 2 diabetes management, Glucagon-like peptide-1 analogues give favourable results, especially in contraindication and metformin intolerance patients, so the use of GLP-1 agonists is highly preferred treatment in lower serum glucose levels or hypoglycemia. In 2023 ADA guidelines said that, alongside lower hypoglycemia and obesity, GLP-1 agonists are highly recommended drugs among patients with clinical ASCVD risks (eg, prior myocardial infarction, stroke), as they lower cardiovascular risk. Similarly, this class of medications were also very beneficial in decreasing chronic kidney disease (CKD).   Now worldwide adult obesity has become a major public health issue in recent years, and alarming obese populations are growing day after day among adults. It could have adverse outcomes and lead to higher morbidity and mortality rates. BMI anthropometric index (earlier called Quetelet index) measurement is commonly globally recognised as a biomarker to assess the risks of obesity.   A higher BMI index has developed many health risk factors; individuals with higher BMI or obese people have triggered some common health issues including premature mortality, cardiac diseases, high BP, worsened osteoarthritis, diabetes and in some cases cancers. Healthy or desirable body weight is highly influenced by daily lifestyles, eating habits, family history or genetics, metabolism rates, and physical activity (level of energy expenditure). However, keeping it well-maintained has become a significant health challenge among millions of people make every effort to achieve desirable results.   Globally, over 2 billion people are affected by obesity issues, which have reached record levels and are putting pressure on public health resources. There is a prevalence of obesity pharmacotherapy interventions or anti-obesity medications have gained attention in different ways to assist in weight loss.    GLP-1 was initially developed to treat type 2 diabetes: Glucagon, a peptide hormone secreted from the alpha cells of the pancreatic islets, plays a major role in glucose metabolism and appetite regulation. Its relationship with Peptide-1 receptor agonist (GLP-1 RA) drugs has gained interest among a large number of people due to their effective therapeutic drug in managing metabolic health. These medications emulate the action of GLP-1, a key hormone released during food intake that contributes to feelings of a state of fullness or leaves you more satiety. Initially, these medications were developed for the treatment of type 2 diabetes mellitus, but GLP-1 RA drugs have demonstrated remarkable outcomes in clinical settings. Studies show that patients can experience significant weight reductions of around 5% to 15% within a year of treatment. This weight loss is not merely an aesthetic benefit; it represents a substantial reduction in obesity-related health risks.   These GLP-1 agonists — now commonly referred to as anti-obesity drugs — have been making large-scale trajectories in weight-loss results, and the need for such solutions has been so urgent. According to the CDC (Centers for Disease Control and Prevention), the prevalence of obese population in the U.S. has surged alarmingly from 30.5% in 1999–2000 over 41.9% in 2017–2020. This staggering increase highlights a critical public health issue that demands immediate attention. Similarly, adult obesity rates in England have put us in another shock! In 2022, a Health Survey for England (HSE) report has completely caught off our guard. The findings are a wake-up call that we cannot afford to ignore. That estimated 28% of adults are classified as obese and another 36% as overweight, the public health has gone through major challenges. On an alarming note, men are at greater risk (67% of men are falling into these categories, compared to 61% of women) more likely than women. Understanding obesity requires more than just numbers; it is vital to grasp its definition—specifically, obesity is defined as a body mass index (BMI) is ≥30. Slightly different from “overweight’, where BMI ranges fall between 25 kg/m² and 30 kg/m² per person. Source: NHS Digital, Health Survey for England 2022, Between 1993 and 2022, the percentage of overweight or obese adults in England increased from 52.9% to 64.3%, and obese adults rose from 14.9% to 28.9%. As the popularity of GLP-1 receptor agonists (GLP-1 RAs) continues to rise, over 15 million obese patients are getting benefits. Forecasts suggest that by the end of this decade, over 30 million Americans will embrace GLP-1 RA treatments to combat obesity and its associated health risks. In European countries, overweight and obesity categories have massively reached an epidemic stage, which is more predominantly observed in men (63%) than women (54%). Wealthier nations often have higher prevalence rates, while the Mediterranean and Eastern European countries show the most overweight and obese people.  What are the applications of Glucagon-like peptide-1 (GLP-1) agonists?   As mentioned earlier, pharmacological use of GLP-1 agonists is primarily taken to treat T2D and obesity, and they have impactful effects to achieve in desired results to regulate plasma glucose levels, they also reduce hunger and suppress daily calorie intake.        How do GLP-1 agonists help our body control obesity and treat patients with T2DM? Let’s understand below, how does GLP-1 hormone work. Your small intestine produces the hormone GLP-1. Among its many roles are: Stimulate insulin secretions from your pancreas: Insulin is an anabolic hormone that converts your food into (a source of) energy in your body. It lowers hyperglycemia ( blood glucose) effects and allows glucose to enter into cells. If your body can’t produce enough insulin, your blood sugar spikes rapidly (hyperglycemia), causing you to have diabetes. Blocking glucagon action: This GLP-1 helps you prevent instant blood sugar spikes and control glucose homeostasis or blocks glucose transport into your bloodstream.   Reduce appetite: Trigger slow digestible carbohydrate activities, which means your body gets less plasma glucose

Share Buy on International Women’s Day discounts on supplements UK from a leading vegan supplement brand – for the entire month of March at 40% OFF. Have you ever stopped to think more deeply about the incredible women in your life and how they juggle responsibilities, care for others in all spheres of life, and still find ways to shine? International Women’s Day on March 8th is a special occasion to honour social, economic, and cultural diversity, we praise the achievements of women to advocate equality of the sexes. All women are socially valued wonderful creatures on earth and deserve to be looked upon equally. It all begins with filling the gaps in the consequent paucity of women. Let’s toast this remarkable global celebration day for all women ‘International Women’s Day 2025’ on the theme of “For ALL women and girls: Rights. Equality. Empowerment.” it’s an annual ceremony of women’s contributions to building our rich cultural heritage, outset history of remembrance, and society as we all walk through life and go after the widely-shared belief “favours men over women”, we believe it should annihilate. It is also a day to glorify womanism, her health, her beauty, her strength and her elegance, to all the women around us. Supremo Nutrition’s healthy nutrition vitamins and supplements store online has always talked about women’s nutrition, we tend to empower women and their overall well-being, and they should be treated equally under the people’s eye, in an exciting – and exclusive for all women to get thrive – so women’s daily nutritional needs is on high priority. Many women are susceptible to malnutrition! 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Women are often the backbone of their families, and they dedicate their energy to nurture and support others. It is your birthright to be healthy, strong, and feel energetic throughout your day. As a strong advocate for plant-based healthy nutrition supplement suppliers across the globe, we encourage you to add your healthy diet with proper nutrition. 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